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1

Screening for mutations causing X-linked severe combined immunodeficiency in the IL-2Rγ chain gene by single-strand conformation polymorphism analysis

Paula A. Clark, Tracy Lester, Sally Genet, Alison M. Jones, Rudi Hendriks, Roland J. Levinsky, Christine Kinnon

Journal:

Year:

1995

Language:

english

File:

PDF, 894 KB

english, 1995

2

Gene therapy: has it delivered what it promised?

Kinnon, Christine

Journal:

British Journal of Hospital Medicine

Year:

2006

Language:

english

File:

PDF, 88 KB

english, 2006

3

Bone morphogenetic protein-4 (BMP4) up regulates key haematopoietic genes in differentiating embryonic stem cells treated with BMP4 short hairpin RNA

Anil Abeyewickreme, Adrian J. Thrasher, Christine Kinnon

Journal:

British Journal of Haematology

Year:

2011

Language:

english

File:

PDF, 234 KB

english, 2011

4

The technique of pulsed field gel electrophoresis and its impact on molecular immunology

Marie-Anne J. O'Reilly, Christine Kinnon

Journal:

Journal of Immunological Methods

Year:

1990

Language:

english

File:

PDF, 1.14 MB

english, 1990

5

Enhancement of integrin-mediated transfection of haematopoietic cells with a synthetic vector system

Aima Uduehi, Carolina Mailhos, Hazel Truman, Adrian J. Thrasher, Christine Kinnon, Stephen L. Hart

Journal:

Biotechnology and Applied Biochemistry

Year:

2003

Language:

english

File:

PDF, 135 KB

english, 2003

6

Cyclooxygenase-2 Overexpression, Using an Integrin-Targeted Gene Delivery System (the LID Vector), Inhibits Fibroblast Proliferation In Vitro and Leads to Increased Prostaglandin E2 in the Lung

Jenkins, Gisli, Hart, Stephen L., Hodges, Rebecca J., Meng, Qin-Hai, Kinnon, Christine, Laurent, Geoffrey J., McAnulty, Robin J.

Journal:

Year:

2002

Language:

english

File:

PDF, 208 KB

english, 2002

7

Coated vesicle preparations contain lymphocyte glycoproteins

KINNON, CHRISTINE, OWEN, MICHAEL J.

Journal:

Biochemical Society Transactions

Year:

1982

Language:

english

File:

PDF, 372 KB

english, 1982

8

Non-viral, integrin-mediated gene transfer into fibroblasts from patients with lysosomal storage diseases

Elaine Joanna Estruch, Stephen Lewis Hart, Christine Kinnon, Bryan G. Winchester

Journal:

The Journal of Gene Medicine

Year:

2001

Language:

english

File:

PDF, 168 KB

english, 2001

9

The synthesis and expression of HLA-A and -B antigens in Xenopus laevis oocytes

Christine Kinnon, Michael J. Owen

Journal:

Molecular Immunology

Year:

1986

Language:

english

File:

PDF, 1.59 MB

english, 1986

10

Mutation analysis in CD40 ligand deficiency leading to X-linked hypogammaglobulinemia with hyper IgM syndrome

Fay Katz, Steve Hinshelwood, Paul Rutland, Alison Jones, Christine Kinnon, Gareth Morgan

Journal:

Year:

1996

Language:

english

File:

PDF, 680 KB

english, 1996

11

The lymphocyte membrane

Mary Collins, Christine Kinnon

Journal:

Immunology Today

Year:

1984

Language:

english

File:

PDF, 397 KB

english, 1984

12

Improvement of Migratory Defects in a Murine Model of Wiskott–Aldrich Syndrome Gene Therapy

Blundell, Michael P, Bouma, Gerben, Calle, Yolanda, Jones, Gareth E, Kinnon, Christine, Thrasher, Adrian J

Journal:

Molecular Therapy

Year:

2008

Language:

english

File:

PDF, 889 KB

english, 2008

13

Expression of Bruton's tyrosine kinase protein within the B cell lineage

Helen C. Genevier, Steve Hinshelwood, Hubert B. Gaspar, Kevin P. Rigley, Derek Brown, Sem Saeland, Francoise Rousset, Roland J. Levinsky, Robin E. Callard, Christine Kinnon, Ruth C. Lovering

Journal:

European Journal of Immunology

Year:

1994

Language:

english

File:

PDF, 620 KB

english, 1994

14

Physical mapping identifies DXS265 as a useful genetic marker for carrier detection and prenatal diagnosis of X-linked agammaglobulinemia

Ruth Levering, Angela K. Sweatman, Marie-Anne J. O'Reilly, Sally A. Genet, Helen Middleton-Price, Sue Malcolm, Roland J. Levinsky, Christine Kinnon

Journal:

Year:

1993

Language:

english

File:

PDF, 284 KB

english, 1993

15

The protein defective in X-linked agammaglobulinemia, Bruton's tyrosine kinase, shows increased autophosphorylation activity in vitro when isolated from cells in which the B cell receptor has been cross-linked

Steve Hinshelwood, Ruth C. Lovering, Helen C. Genevier, Roland J. Levinsky, Christine Kinnon

Journal:

European Journal of Immunology

Year:

1995

Language:

english

File:

PDF, 624 KB

english, 1995

16

Gene therapy of inherited immunodeficiencies

Santilli, Giorgia, Thornhill, Susannah I, Kinnon, Christine, Thrasher, Adrian J

Journal:

Expert Opinion on Biological Therapy

Year:

2008

Language:

english

File:

PDF, 1.09 MB

english, 2008

17

High-Level Transduction and Gene Expression in Hematopoietic Repopulating Cells Using a Human Imunodeficiency Virus Type 1-Based Lentiviral Vector Containing an Internal Spleen Focus Forming Virus Promoter

Demaison, Christophe, Parsley, Kathryn, Brouns, Gaby, Scherr, Michaela, Battmer, Karin, Kinnon, Christine, Grez, Manuel, Thrasher, Adrian J.

Journal:

Human Gene Therapy

Year:

2002

Language:

english

File:

PDF, 284 KB

english, 2002

18

Intrinsic dendritic cell abnormalities in Wiskott-Aldrich syndrome

Michael Binks, Gareth E. Jones, Paul M. Brickell, Christine Kinnon, David R. Katz, Adrian J. Thrasher

Journal:

European Journal of Immunology

Year:

1998

Language:

english

File:

PDF, 150 KB

english, 1998

19

The impact of retroviral suicide gene transduction procedures on T cells

Waseem Qasim, Douglas King, Jo Buddle, Stephanie Verfuerth, Christine Kinnon, Adrian J. Thrasher, Hubert B. Gaspar

Journal:

British Journal of Haematology

Year:

2003

Language:

english

File:

PDF, 516 KB

english, 2003

20

Adeno-Associated Virus Gene Transfer to Mouse Retina

Ali, Robin R., Reichel, Martin B., De Alwis, Mahesh, Kanuga, Naheed, Kinnon, Christine, Levinsky, Roland J., Hunt, David M., Bhattacharya, Shomi S., Thrasher, Adrian J.

Journal:

Human Gene Therapy

Year:

1998

Language:

english

File:

PDF, 7.25 MB

english, 1998

21

Lentiviral Vectors for T-cell Suicide Gene Therapy: Preservation of T-cell Effector Function After Cytokine-mediated Transduction

Qasim, Waseem, Mackey, Taylor, Sinclair, Jo, Chatziandreou, Ilenia, Kinnon, Christine, Thrasher, Adrian J, Gaspar, H Bobby

Journal:

Molecular Therapy

Year:

2007

Language:

english

File:

PDF, 182 KB

english, 2007

22

Polarized expression of bone morphogenetic protein-4 in the human aorta-gonad-mesonephros region

Marshall, Caroline J., Kinnon, Christine, Thrasher, Adrian J.

Journal:

Year:

2000

File:

PDF, 181 KB

2000

23

Detailed characterization of the human aorta-gonad-mesonephros region reveals morphological polarity resembling a hematopoietic stromal layer

Caroline J. Marshall, Rachel L. Moore, Peter Thorogood, Paul M. Brickell, Christine Kinnon, Adrian J. Thrasher

Journal:

Developmental Dynamics

Year:

1999

Language:

english

File:

PDF, 727 KB

english, 1999

24

Is Wiskott–Aldrich syndrome a cell trafficking disorder?

Adrian J Thrasher, Gareth E Jones, Christine Kinnon, Paul M Brickell, David R Katz

Journal:

Immunology Today

Year:

1998

Language:

english

File:

PDF, 144 KB

english, 1998

25

Isolation and mapping of discrete DXS101 loci in Xq22 near the X-linked agammaglobulinaemia gene locus

Marie-Anne J. O'Reilly, Angela K. Sweatman, Linda D. Bradley, Lesley A. Alterman, Ruth Lovering, Sue Malcolm, Roland J. Levinsky, Christine Kinnon

Journal:

Year:

1993

Language:

english

File:

PDF, 390 KB

english, 1993

26

Capture and generation of adenovirus specific T cells for adoptive immunotherapy

Ilenia Chatziandreou, Kimberly C. Gilmour, Anne-Marie McNicol, Maurizio Costabile, Joanna Sinclair, David Cubitt, John D. M. Campbell, Christine Kinnon, Waseem Qasim, H. Bobby Gaspar

Journal:

British Journal of Haematology

Year:

2007

Language:

english

File:

PDF, 659 KB

english, 2007

27

Bone morphogenetic protein 4 modulates c-Kit expression and differentiation potential in murine embryonic aorta-gonad-mesonephros haematopoiesis in vitro

Caroline J. Marshall, Joanna C. Sinclair, Adrian J. Thrasher, Christine Kinnon

Journal:

British Journal of Haematology

Year:

2007

Language:

english

File:

PDF, 502 KB

english, 2007

28

Identification of a donor splice site mutation leading to loss of p22-phox exon 5 in autosomal chronic granulomatous disease

Colin D. Porter, Mohamed H. Parkar, Christine Kinnon

Journal:

Year:

1996

Language:

english

File:

PDF, 118 KB

english, 1996

29

Carrier determination for X-linked agammaglobulinemia using X inactivation analysis of purified B cells

Lesley A. Alterman, Mahesh de Alwis, Sally Genet, Ruth Lovering, Helen Middleton-Price, Gareth Morgan, Alison Jones, Sue Malcolm, Roland J. Levinsky, Christine Kinnon

Journal:

Journal of Immunological Methods

Year:

1993

Language:

english

File:

PDF, 431 KB

english, 1993

30

Diagnosis of X-linked lymphoproliferative disease by analysis of SLAM-associated protein expression

Kimberly C. Gilmour, Treena Cranston, Alison Jones, E. Graham Davies, David Goldblatt, Adrian Thrasher, Christine Kinnon, Kim E. Nichols, Hubert B. Gaspar

Journal:

European Journal of Immunology

Year:

2000

Language:

english

File:

PDF, 107 KB

english, 2000

31

Intrinsic defects of B cell function in X-linked severe combined immunodeficiency

Harry White, Adrian Thrasher, Paul Veys, Christine Kinnon, Hubert B. Gaspar

Journal:

European Journal of Immunology

Year:

2000

Language:

english

File:

PDF, 117 KB

english, 2000

32

Characterization of the murine heat-stable antigen: An hematolymphoid differentiation antigen defined by the J11d, M1/69 and B2A2 antibodies

Lesley A. Alterman, I. Nicholas Crispe, Christine Kinnon

Journal:

European Journal of Immunology

Year:

1990

Language:

english

File:

PDF, 692 KB

english, 1990

33

Genetic mapping of two loci, DXS454 and DXS458, with respect to the X-linked agammaglobulinemia gene locus

Mohammed Parkar, Ruth Lovering, Roland J. Levinsky, Christine Kinnon

Journal:

Year:

1994

Language:

english

File:

PDF, 160 KB

english, 1994

34

10.1038/77068

Ali, Robin R., Sarra, Gian-Marco, Stephens, Clare, Alwis, Mahesh de, Bainbridge, James W.B., Munro, Peter M., Fauser, Sascha, Reichel, Martin B., Kinnon, Christine, Hunt, David M., Bhattacharya, Shomi

Journal:

Nature Genetics

Year:

2000

Language:

english

File:

PDF, 1.07 MB

english, 2000

35

Detection of gp91- phox precursor protein in B-cell lines from patients with X-linked chronic granulomatous disease as an indicator for mutations impairing cytochrome b 558 biosynthesis

PORTER, Colin D., KURIBAYASHI, KURIBAYASHI, PARKAR, Mohamed H., ROOS, Dirk, KINNON, Christine

Journal:

Biochemical Journal

Year:

1996

Language:

english

File:

PDF, 309 KB

english, 1996

36

Enhancement of mouse hematopoietic stem/progenitor cell function via transient gene delivery using integration-deficient lentiviral vectors .

Alonso-Ferrero, Maria E., van Til, Niek P., Bartolovic, Kerol, Mata, Márcia F., Wagemaker, Gerard, Moulding, Dale, Williams, David A., Kinnon, Christine, Waddington, Simon N., Milsom, Michael D., Howe

Journal:

Experimental Hematology

Year:

2017

Language:

english

File:

PDF, 1.34 MB

english, 2017

37

Quality of Repopulation in Nonobese Diabetic Severe Combined Immunodeficient Mice Engrafted With Expanded Cord Blood CD34+ Cells

Blundell, Michael P., Demaison, Christophe, Brouns, Gaby, Goldman, Jacki P., Gaspar, Hubert B., Kinnon, Christine, Thrasher, Adrian J., Lazzari, Lorenza, Sirchia, Girolamo

Journal:

Year:

1999

File:

PDF, 106 KB

1999

38

Physical mapping in the region of the Bruton's tyrosine kinase and α-galactosidase A gene loci in proximal Xq22

Angela K. Sweatman, Linda A. D. Bradley, Ruth C. Lovering, Marie-Anne J. O'Reilly, Roland J. Levinsky, Christine Kinnon

Journal:

Year:

1994

Language:

english

File:

PDF, 427 KB

english, 1994

39

Enhanced human cell engraftment in mice deficient in RAG2 and the common cytokine receptor γ chain

Jacki P. Goldman, Michael P. Blundell, Christine Kinnon, James P. DiSanto, Adrian J. Thrasher

Journal:

Molecular Immunology

Year:

1998

File:

PDF, 268 KB

1998

40

Wiskott-Aldrich Syndrome protein, WASP

Elaine O'Sullivan, Christine Kinnon, Paul Brickell

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

1999

Language:

english

File:

PDF, 141 KB

english, 1999

41

Self-inactivating Gammaretroviral Vectors for Gene Therapy of X-linked Severe Combined Immunodeficiency

Thornhill, Susannah I, Schambach, Axel, Howe, Steven J, Ulaganathan, Meera, Grassman, Elke, Williams, David, Schiedlmeier, Bernhard, Sebire, Neil J, Gaspar, H Bobby, Kinnon, Christine, Baum, Christoph

Journal:

Molecular Therapy

Year:

2008

Language:

english

File:

PDF, 513 KB

english, 2008

42

X-LINKED AGAMMAGLOBULINEMIA

Gaspar, Hubert B., Kinnon, Christine

Journal:

Immunology and Allergy Clinics of North America

Year:

2001

Language:

english

File:

PDF, 1.59 MB

english, 2001

43

Absence of Expression of the Wiskott–Aldrich Syndrome Protein in Peripheral Blood Cells of Wiskott–Aldrich Syndrome Patients

Lucy MacCarthy-Morrogh, Hubert B. Gaspar, Yi-chien Wang, Fay Katz, Lisa Thompson, Mark Layton, Alison M. Jones, Christine Kinnon

Journal:

Clinical Immunology and Immunopathology

Year:

1998

Language:

english

File:

PDF, 159 KB

english, 1998

44

Enhancer-deleted retroviral vectors restore high levels of superoxide generation in a mouse model of CGD

Oliver Schwickerath, Gaby Brouns, Adrian Thrasher, Christine Kinnon, Jürgen Roes, Colin Casimir

Journal:

The Journal of Gene Medicine

Year:

2004

Language:

english

File:

PDF, 418 KB

english, 2004

45

Physical mapping in the region of human Xq12-21.1 using pulsed field gel electrophoresis

Alison M. Jones, Sue Malcolm, Roland J. Levinsky, Christine Kinnon

Journal:

Year:

1993

Language:

english

File:

PDF, 365 KB

english, 1993

46

A Defined Window for Efficient Gene Marking of Severe Combined Immunodeficient-Repopulating Cells Using a Gibbon Ape Leukemia Virus-Pseudotyped Retroviral Vector

Demaison, Christophe, Brouns, Gaby, Blundell, Michael P., Goldman, Jacki P., Levinsky, Roland J., Grez, Manuel, Kinnon, Christine, Thrasher, Adrian J.

Journal:

Human Gene Therapy

Year:

2000

Language:

english

File:

PDF, 239 KB

english, 2000

47

Biochemical Correction of X-CGD by a Novel Chimeric Promoter Regulating High Levels of Transgene Expression in Myeloid Cells

Santilli, Giorgia, Almarza, Elena, Brendel, Christian, Choi, Uimook, Beilin, Chiara, Blundell, Michael P, Haria, Sneha, Parsley, Kathryn L, Kinnon, Christine, Malech, Harry L, Bueren, Juan A, Grez, Ma

Journal:

Molecular Therapy

Year:

2011

Language:

english

File:

PDF, 546 KB

english, 2011

48

665. Novel Gammaretroviral Vectors for Gene Therapy of SCID-X1

Bailey, Susannah I., Howe, Steven J., Schambach, Axel, Kinnon, Christine, Baum, Christopher, Thrasher, Adrian J.

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 91 KB

english, 2006

49

Mutation analysis in Bruton's tyrosine kinase, the X-linked agammaglobulinaemia gene, including identification of an insertional hotspot

Gaspar, Hubert B., Bradley, Linda A.D., Katz, Fay, Lovering, Ruth C., Roifman, Chaim M., Morgan, Gareth, Levinsky, Roland J., Kinnon, Christine

Journal:

Human Molecular Genetics

Year:

1995

Language:

english

File:

PDF, 235 KB

english, 1995

50

The SH3 domain of Bruton's tyrosine kinase displays altered ligand binding properties when auto-phosphorylated in vitro

Lucy MacCarthy Morrogh, Steve Hinshelwood, Patrick Costello, Giles O. C. Cory, Christine Kinnon

Journal:

European Journal of Immunology

Year:

1999

Language:

english

File:

PDF, 189 KB

english, 1999

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